Primary Ciliary Dyskinesia (PCD) is a rare genetic disease

Cilia are common structures throughout the body, so PCD may affect other organs, for example leading to situs inversus, congenital heart defects and infertility. 
Mutations in more than 50 different genes have been identified to date, accounting for approximately 70% of PCD.

Cilia that line the mucosal surface are dysfunctional and cannot clear mucus leading to neonatal respiratory distress, persistent daily wet cough, recurrent upper and lower airway infections, bronchiectasis, hearing impairment and persistent rhino-sinusitis.